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The Journal

Peptide science, one system at a time.

Plain-language articles drawn from the Targeted Peptide Systems books: the reasoning behind protocols, the mistakes people make, and what the current research does and doesn’t show. Every article cites its sources and the book pages it comes from. None of it is dosing advice.

Latest articles

Repair

The Immune Rules Most Peptide Protocols Ignore

Why BPC-157, TB-500 and GHK-Cu underperform in inflamed tissue, and the four immune rules that fix protocol design.

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Repair

Peptide Protocol Sequencing: Why the Order Matters More Than the Stack

Healing runs in phases, and each compound has one where it helps most. Five sequencing principles, explained plainly.

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Repair

Why Regenerative Peptides Don’t Work: The Cellular Battery Problem

Repair runs on cellular energy. What happens when mitochondria decline, and what SS-31, MOTS-c, Humanin and NAD+ are meant to address.

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Repair

Leaky Gut and Systemic Inflammation: The Peptides That Protect the Gut Lining

How a weakened gut barrier drives inflammation body-wide, how the microbiome shapes immune tolerance, and where BPC-157 and KPV fit.

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Metabolic

Metabolism Is an Information System: Retatrutide, GHRH vs GHRP, and the Logic of Stacking

How retatrutide works, the real difference between GHRH and GHRP, and why adding GH peptides too early backfires.

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Browse by system

Repair

Tissue repair and recovery

Immune regulation, sequencing, the gut barrier and cellular energy. Companion articles to Regenerative Resilience.

Metabolic

Metabolism and body composition

Incretins, the growth hormone axis and mitochondrial signalling. Companion articles to Metabolic Precision.

Want the whole framework?

The articles are starting points. The books hold the full reasoning, compound profiles and case models.

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Educational information only, not medical advice. Published by NuTide Paradigm.